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Victims of Tasigna injuries have until September 2018 to file a Tasigna lawsuit against drug manufacturer Novartis. Attorneys need time to gather the evidence for your claim. Contact an attorney as soon as possible to get your case filed in time. The first Tasigna Lawsuit will go to court in October. If you or a loved one has taken Tasigna to treat chronic myeloid leukemia and suffered a life-threatening side effect such as atherosclerosis, contact The Carlson Law Firm to speak with a qualified Tasigna Injury Attorney.
Recently, evidence has shown the blood cancer drug, Tasigna, is linked to atherosclerosis, a condition that refers to the narrowing of arteries. Atherosclerosis may lead to a heart attack, stroke or internal bleeding if the condition isn’t caught in a timely manner. If you or a loved one suffered injuries from taking Tasigna, you may be eligible to receive compensation for your injuries. Contact us to schedule your free, no-obligation consultation with a qualified Tasigna Injury Attorney. The Carlson Law Firm has more than 40 years helping clients who were victims of dangerous drugs.
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What is Tasigna?
Tasigna is an oral cancer drug that treats the blood cancer chronic myeloid leukemia. The drug is a tyrosine kinase inhibitor (TKI) that works by blocking proteins that make cancer cells grow. It is also available as a generic under the name nilotinib. It was first approved in 2008 to treat Philadelphia chromosome-positive chronic myelogenous leukemia (CML).
Swiss multinational pharmaceutical company Novartis developed the drug to replace its cancer drug Gleevec. This drug treated CML and acute lymphocytic leukemia and generated $4.7 billion in sales worldwide.
The company’s researchers found that the drug helped a small number of those who have Parkinson’s and Alzheimer’s disease. It’s hoping to expand the use of the drug beyond CML.
If you or a loved one suffered injuries from taking Tasigna to treat your CML condition, contact The Carlson Law Firm. We offer free, no-obligation consultations and work on a contingency basis. Contact a Tasigna Injury Attorney to schedule your free consultation before the Tasigna Lawsuit deadline is up.
What is Chronic Myelogenous Leukemia?
CML is a form of cancer that affects white blood cells and bone marrow. The disease usually happens in those who are middle-aged or older. It starts as a problem in the genes when sections of two different chromosomes switch places and make an abnormal one. This new chromosome leads your body to make white blood cells that don’t work as they should. These are called leukemia cells. When leukemia cells are present in your bloodstream, there is less room for healthy blood cells.
What are the symptoms of Chronic Myelogenous Leukemia?
Symptoms occur gradually and may sometimes be confused with symptoms of other illnesses. The condition has three phases:
This is the earliest stage and the easiest to treat. In some cases, symptoms are not present.
During this stage, the number of blood cells that don’t work right increases. Because of this increase, a patient is likely to exhibit the following symptoms:
- Easily bruising
- Night sweats
- Shortness of breath
- Unintended weight loss
- Loss of appetite
- Swelling or pain on your left side (sign of an enlarged spleen)
- Feeling pain in the bones
This is the most severe stage of them all. Leukemia cells multiply and crowd out healthy blood cells platelets. Additionally, a patient will have more severe symptoms including:
- Skin changes, including bumps and tumors
- Swollen glands
- Significant bone pain
How is CML Diagnosed?
If you present with these symptoms, doctors will want to run tests to confirm that you have chronic myelogenous leukemia. Possible tests to confirm a CML diagnosis include:
- Complete blood count. This is a blood test that checks how many white blood cells, red blood cells and platelets are present.
- Bone marrow test. Figures out how advanced your cancer is. Your doctors use a needle to take a sample of your bone marrow from your hip bone.
- Fluorescence in Situ Hybridization (FISH) test. A detailed lab test of your genes.
- Ultrasound or CT scans. Either of these tests allows doctors to check the size of your spleen.
- Polymerase chain reaction test. This is a lab test that looks for BCR-ABL gene. This is gene is involved in the process that tells your body to make too many of the wrong kind of white blood cells.
How is CML Treated?
The goal of CML treatment is to destroy the leukemia blood cells and restore healthy ones to a normal level. It’s usually impossible to get rid of all the bad cells. If treatment is received during the earlier stages, it can prevent the disease from moving to more serious levels.
Doctors use TKIs to slow down the rate that a patient’s body makes leukemia cells. Commonly used TKIs include:
Also, doctors will prescribe other drugs if any of these don’t help a patient’s condition or makes a patient too sick. For example, if your condition doesn’t improve after using or two or more TKIs, your doctor may suggest a drug called omacetaxine mepesuccinate (Synribo). Synribo is an injection that is specifically for patients who cannot tolerate other TKIs.
Other Treatments for CML
Other options for treating CML include chemotherapy and biologic therapy. Both of these use a medication called interferon to help jump-start your body’s immune system. Interferon is the same as a protein that the body naturally produces. In the body, it is thought to work by affecting cell function and growth in the body’s natural defenses immune system in many ways. Adding more interferon helps your body fight off cancer or viral infections. It is injected into the muscle or under the skin.
In other patients, a stem cell transplant may be the option for treatment. Stem cell transplants are complicated procedures that are usually done when other treatments have failed. These are cells that live in your bone marrow and help make new blood cells.
Receiving a stem cell transplant requires a donor to supply the new stem cells. Often patients are on a waiting list until they find a donor that is the right match. Your body can reject any stem cells that are not a good match. Typically, close relatives such as your brother or sister are the best chances for a good match.
Why are people filing Tasigna Lawsuits?
Although Tasigna is an effective treatment for CML, it has deadly side effects. Those using Tasigna will experience nausea, fatigue, constipation, joint pain, night sweats, diarrhea, and fever. These symptoms usually proceed signs that point to blood vessel weakness, known as atherosclerosis.
What is Atherosclerosis?
Atherosclerosis is a disease that involves the hardening and narrowing of arteries. Also, these actions put blood flow at risk. The condition is characterized by the buildup of plaques of fatty material on the inner walls of the arteries. It is the cause of the three main kinds of cardiovascular disease:
- Coronary artery disease: This condition leads to a heart attack. Stable plaques in the heart’s arteries cause chest pain. A sudden plaque rupture and clotting cause heart muscle to die.
- Cerebrovascular disease: Ruptured plaques in the brain’s arteries cause strokes with the potential for permanent brain damage. Temporary blockages in the arteries lead to transient ischemic attacks (TIAs), which are warning signs of a stroke. However, in these cases there is no brain injury.
- Peripheral artery disease: Narrowing in the arteries of the legs from plaque causes poor circulation. This makes it painful to walk. The condition often causes wounds to heal slowly or not as well. Severe disease may lead to amputations.
If you or a loved one developed atherosclerosis, contact a Tasigna Injury Attorney from The Carlson Law Firm. We have a team ready to help you file your Tasigna Lawsuit.
Why is Tasigna a Dangerous Drug?
Researchers have found links between Tasigna and atherosclerosis. Atherosclerosis leads to plaque build up inside the arteries. It may cause harm to the arteries in the body including the arteries in the arms, legs, brain, heart, and kidney.
Complications stemming from Tasigna use have common side effects like:
- Low blood count
- Muscle and joint point
In some cases, these effects lead to more serious injuries like liver damages, bleeding in the brain, kidney failure, and blood in urine. Further injuries include:
- Pancreas inflammation
- Bleeding in the brain
- Tumor Lysis Syndrome (TLS), which can cause kidney failure
- Decrease blood flow to the legs, heart or brain
- Low blood count in conjunction with unexplained bleeding, blood in the urine and unexplained weakness
- QT prolongation that can cause sudden death
What is Tasigna’s link with Atherosclerosis?
The first major study linking Tasigna with atherosclerosis was published in 2011. The research found that some patients taking the drug experienced vascular problems. Subsequent studies show that Tasigna accelerated atherosclerosis.
Additionally, atherosclerosis is a side effect not currently listed on the U.S. warning label for Tasigna. As mentioned above, the disease results in a build up in the arteries which causes the arteries to harden and narrow blood flow pathways. The limiting of blood flow that the disease causes can lead to a host of diseases and death. However, patients taking the medication and the doctors prescribing it were unaware of the deadly side effect.
For these reasons, patients are filing Tasigna Lawsuits against Novartis. If you suffered injury or a loved one died from taking the medication, contact The Carlson Law Firm to schedule a free consultation with a Tasigna Injury Attorney. We can help you file a Tasigna lawsuit and recover the compensation you’re entitled to.
Did Novartis Issue a Warning About Tasigna’s Link to Atherosclerosis?
No, Novartis did not issue a warning about Tasigna’s link to atherosclerosis to the U.S. market. However, in 2013, the company in conjunction with Health Canada release a warning the cases of atherosclerosis-related conditions were being reported in clinical trials and post-marketing experience for the drug.
According to the Canadian announcement, a global review between 2005 and 2013 found 277 cases of atherosclerosis with Tasigna. Further, the information was added to a reference document for healthcare professionals in Canada and the consumer information leaflet.
Despite these findings, patients and professional in the U.S. remained unaware of the dangerous side effects of the drug. The company never issued a warning to the U.S. through the FDA.
Contact a Carlson Law Firm Tasigna Injury Attorney to discuss your possible Tasigna Lawsuit.
When was the first Tasigna Lawsuit Filed?
The first Tasigna Lawsuit was filed in March 2016. The family of a California man who died from atherosclerosis after taking Tasigna filed a wrongful death lawsuit against Novartis. The lawsuit alleges that the company failed to warn consumers about the dangers associated with the drug. The lawsuit prompted the filing of similar lawsuits that allege Novartis:
- Did not send advisories to the U.S. public or U.S. doctors about the drug’s dangerous side effects.
- Did not properly warn of the arteriosclerosis-related risks on the U.S. Tasigna label.
- The company’s failure to warn U.S. doctors and patients of the serious risks of developing atherosclerosis-related condition was intentional.
- Part of an aggressive marketing strategy to sell Tasigna over competing TKIs.
- The company knew as early as 2011 of the link between its drug and atherosclerosis.
If patients or doctors knew of the possibility of developing atherosclerosis, they may have opted to use a different CML treatment. Patients who suffered a Tasigna injury or who lost a loved one because of Novartis’ negligence may be eligible to receive compensation for their injuries or loss. Contact a Tasigna Injury Attorney to discuss your case. The Carlson Law Firm can help you determine if filing a Tasigna lawsuit is the right option for you. We offer free, no obligation consultations.
Past problems with Tasigna
Mounting Tasigna Lawsuits are not Novartis’ first time trying to sidestep U.S. law and putting citizens at risk. The company has had two other instances of questionable activity in relation to the U.S. market within the last ten years.
Violation of FDA Facebook Advertising Regulations
In 2010, the FDA sent a warning letter to Novartis that the company’s advertising efforts on Facebook violated the agency’s guidance on the use of social media for marketing drugs. Moreover, in the letter, the FDA highlighted several issues with the company’s Tasigna Facebook ads:
Risks. The ads did no adequately inform readers of the risks of taking Tasigna, including the black box warning included on the warning labels.
Indications. The ads incorrectly implied that Tasigna could treat all forms of CML, rather than a subset of people with the disease.
Effectiveness. The company’s ads used terms like “next-generation” to describe Tasigna. The language suggested that the drug was better than similar drugs.
In addition, the FDA’s letter said that the company failed to submit its Facebooks ads for review properly. This is a step that is required by regulation before running ads on social media.
In addition, in 2015 Novartis announced a $390 million settlement with the U.S. Department of Justice over claims of illegal kickbacks to specialty pharmacies. The department of justice sued Novartis in Federal Court because the company illegally sought to boost sales of drugs covered by the U.S. government and backed by Medicare and Medicaid programs. The DOJ initially sued the company for $3.35 billion.
How can a Tasigna Injury Attorney Help Me?
If you or a loved one meet all of the following conditions, you may be eligible to file a Tasigna lawsuit.
- Diagnosed with Ph+ chronic myeloid leukemia
- Prescribed or ingested Tasigna
- Experienced a severe side effect such as atherosclerosis or a condition stemming from it
A Tasigna Injury Attorney can help you understand your legal rights. You may be eligible to receive compensation for your injuries or your loss. Moreover, it is important to contact The Carlson Law Firm immediately as the filing deadline is upon us. Attorneys have a mid-September deadline to get your case in order so that you can receive just compensation.
A Tasigna Injury Attorney can help you recover for both economic and noneconomic damages such as:
- Treatment costs
- Cost of travel to and from medical appointments
- Lost income
- Pain and suffering
- Loss of companionship (consortium)
- Punitive damages
Contact an attorney immediately to get a free consultation with The Carlson Law Firm. There are no upfront costs to you whatsoever. We will work tirelessly on your behalf to recover a fair amount on your behalf. We only receive payment if we successfully recover damages.
The Carlson Difference
Most personal injury law firm consists of individual lawyers who have to bring in investigators and nurses to review your cases. However, the Carlson Law Firm keeps all of those resources in-house. We maintain a team of professionals that include more than 40 experienced lawyers, over 100 qualified and passionate staff, as well as full-time registered and investigators. We are the team to guide you through a Tasigna lawsuit.
Our firm has more than 40 years of experience representing victims of dangerous drugs. If you or someone you love suffered Tasigna injuries, contact The Carlson Law Firm. A qualified Tasigna Injury Attorney can help you recover compensation for your treatment and other expenses you endured as a result of your injuries. We have a team of caring and compassionate Tasigna Injury Attorneys ready to help you with your Tasigna Lawsuit.
You can call, email or chat with us to schedule a free consultation with a Tasigna Injury Attorney.